A retrospective study of anal sac tumours without pulmonary metastases, from the author's clinical records for the period July to July , was conducted to establish the response to treatment with surgery and melphalan chemotherapy. Of 21 dogs with tumours of the anal sacs 19 had apocrine gland adenocarcinomas of anal sac origin, one had a benign papillary cystadenoma and another had a malignant melanoma. Two of the 19 dogs had bilateral anal sac adenocarcinomas. Ten of the 19 dogs with apocrine gland adenocarcinomas of anal sac origin had sublumbar lymphadenopathy. Five dogs were excluded by their owners from recommended treatment. Fourteen dogs with apocrine gland adenocarcinomas of anal sac origin were treated by surgical cytoreduction and chemotherapy with melphalan.
Dogs and cats can function normally without these scent glands. Cancer can develop in the anal sac glands in dogs, but rarely in cats. In most cases, this tumor affects only one anal sac, but occasionally both left and right sacs are affected. Anal sac cancer is usually malignant and has a high tendency to spread to the other body parts. If it spreads, regional lymph nodes and the liver are commonly affected; however, the tumor can also spread to the lungs. Other signs may include a large visible swelling of the anal region, straining during bowel movements, thin ribbon-shaped stools, difficulty passing urine and arching of the back. Anal sac tumors can cause elevation of the calcium level in the blood, which results in increased thirst, increased urination, decreased activity, decreased appetite, weight loss, vomiting, muscle weakness and low heart rate.
Anal sac tumours of the dog and their response to cytoreductive surgery and chemotherapy.
Other treatment modalities include radiotherapy and chemotherapy, but the role of these treatments has not been clearly determined yet. Pre-operative medical support is provided as required. In particular, severe hypercalcaemia of malignancy HM; i. Management of HM is beyond the scope of this text and is widely detailed elsewhere Briefly, it is treated with a combination of fluid therapy 0.
What should I expect from his treatment? Thank you, D. Dear D.